Lunasin was first discovered in 1996 by Dr. Alfredo Galvez as a result of his research to improve the nutritional profile of soy protein in Dr. de Lumen's UC Berkeley lab.
Dr. Galvez realized that this impressive soy peptide, which is found in small quantities in soybean seeds and soy-based foods, blocks cell division by binding to specific chromosomal proteins called "hypoacetylated histones." Because there is consistent epidemiological data regarding soy and cancer prevention, Lunasin was first investigated as a factor that might prevent cancer cells from dividing and multiplying. The mechanism of action for Lunasin and cancer prevention was included in prestigious journals, such as Nature Biotechnology and the Journal of Cancer Research. As Dr. Galvez continued to study Lunasin, it became evident that the soy peptide had another powerful mechanism of action– lowering cholesterol. While soy has long been linked to heart health, recent studies indicate that protection of the lunasin peptide component so that sufficient amounts are bioavailable once inside the body is the key to its ability to lower LDL (bad) cholesterol.